Features such as mouse hover won’t necessarily work and your application could be inoperable. If you’re coding on a regular PC with a mouse and keyboard, it’s difficult to appreciate how your interface will operate. The process is complicated further by touch screens, hybrid devices, and high-density displays. In extreme cases, it could take as long as the original development.
Your latest masterpiece must be rigorously evaluated on a range of mobile, tablet and desktop devices with differing OSs, screen resolutions, and capabilities. The days of checking functionality in a couple of browsers are long gone. Website testing has become increasingly complex.